KSPM
Search
- Page Path
- HOME > Search
Original Articles
- Mortality Burden Due to Short-term Exposure to Fine Particulate Matter in Korea
- Jongmin Oh, Youn-Hee Lim, Changwoo Han, Dong-Wook Lee, Jisun Myung, Yun-Chul Hong, Soontae Kim, Hyun-Joo Bae
- J Prev Med Public Health. 2024;57(2):185-196. Published online March 29, 2024
- DOI: https://doi.org/10.3961/jpmph.23.514
- 977 View
- 38 Download
-
Abstract
Summary
PDF
Supplementary Material - Objectives
Excess mortality associated with long-term exposure to fine particulate matter (PM2.5) has been documented. However, research on the disease burden following short-term exposure is scarce. We investigated the cause-specific mortality burden of short-term exposure to PM2.5 by considering the potential non-linear concentration–response relationship in Korea.
Methods
Daily cause-specific mortality rates and PM2.5 exposure levels from 2010 to 2019 were collected for 8 Korean cities and 9 provinces. A generalized additive mixed model was employed to estimate the non-linear relationship between PM2.5 exposure and cause-specific mortality levels. We assumed no detrimental health effects of PM2.5 concentrations below 15 μg/m3. Overall deaths attributable to short-term PM2.5 exposure were estimated by summing the daily numbers of excess deaths associated with ambient PM2.5 exposure.
Results
Of the 2 749 704 recorded deaths, 2 453 686 (89.2%) were non-accidental, 591 267 (21.5%) were cardiovascular, and 141 066 (5.1%) were respiratory in nature. A non-linear relationship was observed between all-cause mortality and exposure to PM2.5 at lag0, whereas linear associations were evident for cause-specific mortalities. Overall, 10 814 all-cause, 7855 non-accidental, 1642 cardiovascular, and 708 respiratory deaths were attributed to short-term exposure to PM2.5. The estimated number of all-cause excess deaths due to short-term PM2.5 exposure in 2019 was 1039 (95% confidence interval, 604 to 1472).
Conclusions
Our findings indicate an association between short-term PM2.5 exposure and various mortality rates (all-cause, non-accidental, cardiovascular, and respiratory) in Korea over the period from 2010 to 2019. Consequently, action plans should be developed to reduce deaths attributable to short-term exposure to PM2.5. -
SummaryKorean summary
본 연구는 2010~2019년 한국의 초미세먼지 단기 노출로 인한 사망 부담을 추정하였으며 2010~2019년간, 초미세먼지 단기노출로 인한 전체원인 사망은 10,814명, 비사고 사망은 7,855명, 심혈관 사망은 1,642명, 호흡기 사망은 708명으로 추정하였다. 본 연구 결과는 대기오염 관리, 규제, 정책 수립에 있어 도움을 줄 것으로 예상한다.Key Message
- We estimated mortality burden attributable to short-term exposure to PM 2.5 in Korea from 2010 to 2019 - Over the 10-years study period, the estimated excess deaths due to short-term exposure to PM 2.5 totaled 10,814 for all-causes, 7,855 for non-accidental, 1,642 for cardiovascular disease, and 708 for respiratory disease. - Our findings can assist in air pollution management, regulation, and policy-making.
- The Association Between Oxidative Stress and Depressive Symptom Scores in Elderly Population: A Repeated Panel Study
- Changwoo Han, Youn-Hee Lim, Yun-Chul Hong
- J Prev Med Public Health. 2016;49(5):260-274. Published online August 23, 2016
- DOI: https://doi.org/10.3961/jpmph.16.029
- 8,964 View
- 210 Download
- 12 Crossref
-
Abstract
PDFSupplementary Material
- Objectives
Previous epidemiological studies about oxidative stress and depression are limited by hospital-based case-control design, single-time measurements of oxidative stress biomarkers, and the small number of study participants. Therefore, in this study, we analyzed the association between biomarker of oxidative stress and depressive symptom scores using repeatedly measured panel data from a community-dwelling elderly population.
Methods
From 2008 to 2010, a total of 478 elderly participants residing in Seoul, Korea, were evaluated three times. Participants underwent the Korean version of the Short Form Generic Depression Scale (SGDS-K) test for screening depression, and urinary malondialdehyde (MDA) levels were measured as an oxidative stress biomarker. We used a generalized estimating equation with a compound symmetry covariance structure to estimate the effects of oxidative stress on depressive symptom scores.
Results
A two-fold increase in urinary MDA concentration was significantly associated with a 33.88% (95% confidence interval [CI], 21.59% to 47.42%) increase in total SGDS-K scores. In subgroup analyses by gender, a two-fold increase in urinary MDA concentration was significantly associated with increased SGDS-K scores in both men and women (men: 30.88%; 95% CI, 10.24% to 55.37%; women: 34.77%; 95% CI, 20.09% to 51.25%). In bivariate analysis after an SGDS-K score ≥8 was defined as depression, the third and the fourth urinary MDA quartiles showed a significantly increased odds ratio(OR) of depression compared to the lowest urinary MDA quartile (third quartile OR, 6.51; 95% CI, 1.77 to 24.00; fourth quartile OR, 7.11; 95% CI, 1.99 to 25.42).
Conclusions
Our study suggests a significant association between oxidative stress and depressive symptoms in the elderly population. -
Summary
Citations
Citations to this article as recorded by
- Curcumin Ameliorates Neurobehavioral Deficits in Ambient Dusty Particulate Matter-Exposure Rats: The Role of Oxidative Stress
Sadegh Moradi Vastegani, Somayeh Hajipour, Alireza Sarkaki, Zahra Basir, Yaghoob Farbood, Kowsar Bavarsad, Seyed Esmaeil Khoshnam
Neurochemical Research.2023; 48(6): 1798. CrossRef - Evaluation of the Physical Health and Dietary Intake of the Low-Income Elderly with Impaired Mobility for the Design of a Health Meals-on-Wheels Intervention Program in Seoul
Hyeja Chang, Junghyun Kim, Chaewon Park
Journal of the Korean Society of Food Science and Nutrition.2023; 52(7): 740. CrossRef - Can tailored home-delivered meal services alleviate self-rated frailty of the low-income older adults in Korea?
Junghyun Kim, Hyeja Chang
Nutrition Research and Practice.2023; 17(5): 1007. CrossRef - Exploring urinary biomarkers to assess oxidative DNA damage resulting from BTEX exposure in street children
Ata Rafiee, Juana Maria Delgado-Saborit, Peter D. Sly, Hoda Amiri, Mohammad Hoseini
Environmental Research.2022; 203: 111725. CrossRef - Association of ambient air pollution with depressive and anxiety symptoms in pregnant women: A prospective cohort study
Dirga Kumar Lamichhane, Dal-Young Jung, Yee-Jin Shin, Kyung-Sook Lee, So-Yeon Lee, Kangmo Ahn, Kyung Won Kim, Youn Ho Shin, Dong In Suh, Soo-Jong Hong, Hwan-Cheol Kim
International Journal of Hygiene and Environmental Health.2021; 237: 113823. CrossRef - Effects of cholecalciferol on behavior and production of reactive oxygen species in female mice subjected to corticosterone-induced model of depression
Suene Vanessa da Silva Souza, Priscila Batista da Rosa, Vivian Binder Neis, Júlia Dubois Moreira, Ana Lúcia S. Rodrigues, Morgana Moretti
Naunyn-Schmiedeberg's Archives of Pharmacology.2020; 393(1): 111. CrossRef - Air pollution is associated with depressive symptoms in elderly women with cognitive impairment
Hicran Altuğ, Kateryna B. Fuks, Anke Hüls, Anne-Kathrin Mayer, Rachel Tham, Jean Krutmann, Tamara Schikowski
Environment International.2020; 136: 105448. CrossRef - Oxidative stress, antioxidant defense and depressive disorders: A systematic review of biochemical and molecular markers
Maiza Lacerda Barbosa, Ag-Anne Pereira Melo de Meneses, Rai Pablo Sousa de Aguiar, João Marcelo de Castro e Sousa, Ana Amélia de Carvalho Melo Cavalcante, Sharbel Weidner Maluf
Neurology, Psychiatry and Brain Research.2020; 36: 65. CrossRef - Changes in the concentrations of inflammatory and oxidative status biomediators (MIP-1 α, PMN elastase, MDA, and IL-12) in depressed patients with and without posttraumatic stress disorder
Ewa A. Ogłodek
Pharmacological Reports.2018; 70(1): 110. CrossRef - Weight Status, Physical Activity, and Depression in Korean Older Adults
Jinkyung Cho, Youngyun Jin, Hyunsik Kang
Journal of Epidemiology.2018; 28(6): 292. CrossRef - Elevated serum levels of malondialdehyde and cortisol are associated with major depressive disorder: A case-control study
Md Rabiul Islam, Md Reazul Islam, Imtiaz Ahmed, Abdullah Al Moktadir, Zabun Nahar, Mohammad Safiqul Islam, Shelina Fatema Binte Shahid, Sheikh Nazrul Islam, Md Saiful Islam, Abul Hasnat
SAGE Open Medicine.2018; 6: 205031211877395. CrossRef - Conditional Human Immunodeficiency Virus Transactivator of Transcription Protein Expression Induces Depression-like Effects and Oxidative Stress
Jay P. McLaughlin, Jason J. Paris, Dionyssios Mintzopoulos, Kristen A. Hymel, Jae K. Kim, Thomas J. Cirino, Timothy E. Gillis, Shainnel O. Eans, Gordana D. Vitaliano, Jessica M. Medina, Richard C. Krapf, Heather M. Stacy, Marc J. Kaufman
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.2017; 2(7): 599. CrossRef
First
Prev
